What is anabolism of fatty acids?

Anabolism of fatty acids, also known as lipid synthesis, involves the conversion of simple molecules such as glucose into complex molecules known as triglycerides. This process occurs in the liver and adipose tissue.

The anabolism of fatty acids begins with the conversion of glucose into acetyl-CoA through the process of glycolysis. The acetyl-CoA then enters the citric acid cycle, where it is converted into NADH and FADH2, which are used to produce ATP. Acetyl-CoA can also be used to produce fatty acids.

The fatty acids are then activated by attaching them to a molecule called CoA, which allows them to enter the process of lipid synthesis. The fatty acids are then joined together to form triglycerides, which are then packaged into lipoprotein particles called VLDL and transported to adipose tissue.

Anabolism of fatty acids is a complex and regulated process that is influenced by a variety of factors including hormones such as insulin and glucagon, as well as dietary factors such as the types and amounts of fats consumed. It plays a critical role in regulating energy balance and metabolic homeostasis.